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Cysteamine

Cysteamine

Cysteamine · next-generation stable form

Cysteamine is a physiologically active substance naturally present in animals and involved in normal metabolism — an efficient, stable growth solution that works by regulating the animal's own growth axis. Yuanchang's cysteamine uses a stable crystalline process that overcomes the oxidation, moisture absorption, and coating dependence of conventional cysteamine hydrochloride — achieving heat resistance, storage stability, and thorough release.

Mechanism of action

Cysteamine is the decarboxylation product of cysteine and a component of coenzyme A. Its active thiol group chemically modifies somatostatin (SS, a brain-gut peptide), removing its immunological and biological activity — which in turn:

  • Regulates the hypothalamic–pituitary–growth axis, promoting release of growth hormone (GH) and insulin-like growth factor (IGF-1);
  • Raises gastric-juice, pepsin, and pancreatic/intestinal enzyme activity and increases intestinal villus length, improving digestion and absorption;
  • Depletes SS in a dose- and time-dependent, reversible manner — SS levels typically return to normal after about one week.
Diagram of cysteamine regulating the growth axis
How cysteamine coordinates lactation, growth, and immunity ("+" promotes, "−" reduces)

Product features

The thiol group makes conventional cysteamine hydrochloride highly unstable — hygroscopic, readily deliquescent, and easily oxidized in air to sulfur dioxide, sulfinic and sulfonic acids. Cysteamine effectively addresses this through stable crystallization.

Yuanchang cysteamine vs. other cysteamine products
PropertyCysteamineOther cysteamine HCl
Physical structureStable crystalHCl crystal
Oxidation stabilityStableOxidizes to SO₂, sulfinic/sulfonic acids
Physical stabilityStableAbsorbs moisture
Post-processingNo coating neededRequires coating
ReleaseThorough releaseDetermined by coating strength
Stability verified: in long-term room-temperature storage tests, content stayed stable over 16 months; in 140 °C heat tests, content showed essentially no decay over 20 minutes.

Effects by stage

  • Piglets: promotes growth and development, improves daily gain and feed-to-gain ratio, boosts immunity and stress resistance, supports gut microenvironment formation, and reduces diarrhea.
  • Growing pigs: improves growth performance, markedly increases lean-meat percentage, and improves body type and carcass quality.
  • Sows: promotes mammary development, raises prolactin and colostrum immunoglobulin levels, increases feed utilization, and improves milk quality.

Recommended dosage

Application in formulations
StageDosageNotes
Finisher (enhanced)400 g / tonneUse for 30 days before market
Growing–finishing300 g / tonne—
Standard nursery/grower200 g / tonneMay be added long-term as a growth promoter
Lactating sows300 g / tonneFrom one month pre-farrowing until weaning

Safety

Both the FDA and EMEA have approved cysteamine for human use; the EMEA classifies it as an organic substance "requiring no maximum residue limit," suitable for all mammals producing livestock products. Cysteamine has natural activity and safety in animals and participates in normal metabolism.

Formula: C₂H₇NS·HCl　Melting point: 66–70 °C　Appearance: white crystalline powder, soluble in water and ethanol.

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